Analyze biological data using Lobster AI — single-cell RNA-seq, bulk RNA-seq, literature mining, dataset discovery, quality control, and visualization. USE THIS SKILL WHEN: - Analyzing single-cell or bulk RNA-seq data - Searching PubMed/GEO for papers or datasets - Running quality control on biological data - Clustering cells, finding markers, differential expression - Creating publication-quality visualizations - Working with H5AD, CSV, 10X, GEO/SRA accessions TRIGGER PHRASES: "analyze cells", "search PubMed", "download GEO", "run QC", "cluster", "find markers", "differential expression", "UMAP", "volcano plot", "single-cell", "RNA-seq", "bioinformatics" ASSUMES: Lobster is installed and configured. For setup issues, tell user to run `lobster config-test` and fix any errors before proceeding.
数据来源：ClawHub。 在 ClawSkills 查看
选择你使用的 Agent
方法一：命令行安装（推荐）
推荐（无需提前安装 clawhub）
npx clawhub@latest --dir ~/.claude/skills install lobster-bio-use或使用 clawhub CLI（需提前安装）
clawhub --dir ~/.claude/skills install lobster-bio-use⚠️ 需要 Node.js 18+，没有 Node？请使用下方方法二直接下载 ZIP。 安装 Node.js →
方法二：手动下载安装（无需 Node）
下载 ZIP，解压后将文件夹放到以下路径，重启 Agent 即可：
安装路径
~/.claude/skills/lobster-bio-use/💡解压后将文件夹放到上方路径，重启 Agent 即可生效
--- name: lobster-use description: | Analyze biological data using Lobster AI — single-cell RNA-seq, bulk RNA-seq, literature mining, dataset discovery, quality control, and visualization.
USE THIS SKILL WHEN: - Analyzing single-cell or bulk RNA-seq data - Searching PubMed/GEO for papers or datasets - Running quality control on biological data - Clustering cells, finding markers, differential expression - Creating publication-quality visualizations - Working with H5AD, CSV, 10X, GEO/SRA accessions
TRIGGER PHRASES: "analyze cells", "search PubMed", "download GEO", "run QC", "cluster", "find markers", "differential expression", "UMAP", "volcano plot", "single-cell", "RNA-seq", "bioinformatics"
ASSUMES: Lobster is installed and configured. For setup issues, tell user to run lobster config-test and fix any errors before proceeding. ---
Lobster AI is a multi-agent bioinformatics platform. You interact via natural language or slash commands — Lobster routes to specialist agents automatically.
If Lobster is not installed, guide the user to the right command for their platform:
curl -fsSL https://install.lobsterbio.com | bashirm https://install.lobsterbio.com/windows | iexuv tool install 'lobster-ai[full,anthropic]' && lobster init
# or: pip install 'lobster-ai[full]' && lobster initAfter install, lobster init configures API keys and selects agent packages.
uv tool upgrade lobster-aipip install --upgrade lobster-aiUsers with uv tool installs add agents via: uv tool install lobster-ai --with lobster-transcriptomics --with lobster-proteomics Running lobster init will guide this process and generate the command.
| Task | Reference | |------|-----------| | CLI commands | references/cli-commands.md | | Single-cell analysis | references/single-cell-workflow.md | | Bulk RNA-seq analysis | references/bulk-rnaseq-workflow.md | | Literature & datasets | references/research-workflow.md | | Visualization | references/visualization.md | | Available agents | references/agents.md |
lobster chat # Start interactive session
lobster chat --workspace ./myproject # Custom workspace
lobster chat --reasoning # Enable detailed reasoninglobster query "Your request"
lobster query --session-id latest "Follow-up request"Just describe what you want:
"Download GSE109564 and run quality control"
"Cluster the cells and find marker genes"
"Compare hepatocytes vs stellate cells"/data # Show loaded data info
/files # List workspace files
/workspace list # List available datasets
/workspace load 1 # Load dataset by index
/plots # Show generated visualizations
/save # Save current session
/status # Show system status
/help # All commands# Start named session
lobster query --session-id "my_analysis" "Load GSE109564"
# Continue with context
lobster query --session-id latest "Now cluster the cells"
lobster query --session-id latest "Find markers for cluster 3"Lobster routes to specialist agents automatically:
| Agent | Handles | |-------|---------| | Supervisor | Routes queries, coordinates agents | | Research Agent | PubMed search, GEO discovery, paper extraction | | Data Expert | File loading, format conversion, downloads | | Transcriptomics Expert | scRNA-seq: QC, clustering, markers | | DE Analysis Expert | Differential expression, statistical testing | | Annotation Expert | Cell type annotation, gene set enrichment | | Visualization Expert | UMAP, heatmaps, volcano plots | | Proteomics Expert | Mass spec analysis [alpha] | | Genomics Expert | VCF, GWAS, variant analysis [alpha] | | ML Expert | Embeddings, classification [alpha] |
Default workspace: .lobster_workspace/
Output files: | Extension | Content | |-----------|---------| | .h5ad | Processed AnnData objects | | .html | Interactive visualizations | | .png | Publication-ready plots | | .csv | Exported tables | | .json | Metadata, provenance |
Managing outputs:
/files # List all outputs
/plots # View visualizations
/open results.html # Open in browser
/read summary.csv # Preview file contents# 1. Start session
lobster chat --workspace ./my_analysis
# 2. Load or download data
"Download GSE109564 from GEO"
# or
/workspace load my_data.h5ad
# 3. Quality control
"Run quality control and show me the metrics"
# 4. Analysis
"Filter low-quality cells, normalize, and cluster"
# 5. Interpretation
"Identify cell types and find marker genes"
# 6. Visualization
"Create UMAP colored by cell type"
/plots
# 7. Export
"Export marker genes to CSV"
/save| Issue | Check | |-------|-------| | Lobster not responding | lobster config-test | | No data loaded | /data to verify, /workspace list to see available | | Analysis fails | Try with --reasoning flag | | Missing outputs | Check /files and workspace directory |
Online docs: docs.omics-os.com
Key sections:
安装 LobsterBio - Use 后，可以对 AI 说这些话来触发它
Help me get started with LobsterBio - Use
Explains what LobsterBio - Use does, walks through the setup, and runs a quick demo based on your current project
Use LobsterBio - Use to analyze biological data using Lobster AI — single-cell RNA-seq, bul...
Invokes LobsterBio - Use with the right parameters and returns the result directly in the conversation
What can I do with LobsterBio - Use in my data & analytics workflow?
Lists the top use cases for LobsterBio - Use, with example commands for each scenario
将技能文件夹放到 ~/.claude/skills/lobster-bio-use/ 目录（个人级，所有项目可用），或 .claude/skills/lobster-bio-use/（项目级）。重启 AI 客户端后，用 /lobster-bio-use 主动调用，或让 AI 根据上下文自动发现并使用。
LobsterBio - Use 支持 Claude、Cursor、OpenClaw，可与这些 AI 平台无缝集成，扩展其能力。
LobsterBio - Use 可免费安装使用。请查阅仓库了解许可证信息。
Analyze biological data using Lobster AI — single-cell RNA-seq, bulk RNA-seq, literature mining, dataset discovery, quality control, and visualization. USE THIS SKILL WHEN: - Analyzing single-cell or bulk RNA-seq data - Searching PubMed/GEO for papers or datasets - Running quality control on biological data - Clustering cells, finding markers, differential expression - Creating publication-quality visualizations - Working with H5AD, CSV, 10X, GEO/SRA accessions TRIGGER PHRASES: "analyze cells", "search PubMed", "download GEO", "run QC", "cluster", "find markers", "differential expression", "UMAP", "volcano plot", "single-cell", "RNA-seq", "bioinformatics" ASSUMES: Lobster is installed and configured. For setup issues, tell user to run `lobster config-test` and fix any errors before proceeding.
Automate my data & analytics tasks using LobsterBio - Use
Identifies repetitive steps in your workflow and sets up LobsterBio - Use to handle them automatically
LobsterBio - Use 属于「Data & Analytics」分类，该分类的技能帮助 AI 智能体在此领域执行专业任务。